Even though antidepressants is one of the most commonly prescribed classes of drugs in the U.S, choosing the safest one for pregnant patients suffering from depression is challenging. A new research that included 17,952 mothers of infants with birth defects, and 9,857 mothers of infants without birth defects, born between 1997 and 2009 found a link between certain birth defects and Prozac (fluoxetine) and Paxil (paroxetine) when they were used one month before or during the first three months of pregnancy (1st trimester). However, no such link was found with Zoloft (sertraline), Celexa (citalopram) and Lexapro (escitalopram). Overall, weighing the benefits versus the risks between the condition and the possibility of birth defects is crucial in choosing the right antidepressant for pregnant patients. How often do you counsel pregnant women about the risks of their medications? Do these findings supports what you see in your practice?
For additional information please read BMJ.
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