A new study that was presented in November’s scientific conference of the American Heart Association suggests that taking small doses of aspirin at night may be better than taking it in morning. Researchers in the Netherlandsperformed a crossover study randomizing 290 patients with cardiovascular disease to take their 100mg aspirin at bedtime or first thing in the morning during 2 phases of 3 months. Blood pressure and morning platelet activity were measured after each phase. Although timing of aspirin had no effect on blood pressure, platelet activity wasfound to be reduced to a greater extent when aspirin was taken at night which may decrease cardiovascular events in the morning. Based on this study, would you consider recommending aspirin at bedtime to your patients?

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