FDA released a warning letter today that anti-seizure medication ezogabine (Protiga) can cause blue skin discoloration and pigment changes in the retina which may potentially lead to serious eye disease with loss of vision. All patients taking Potiga should have a baseline eye exam followed by periodic eye exams and the medication should be discontinued if ophthalmic changes or skin discoloration occurs. Do you routinely ask patients about adverse effects related to their drug therapy?

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