PR_030-_SI_-_07_06_12-128A study published in the New England Journal of Medicine evaluated the efficacy of weight-loss intervention in patients with serious mental illness, such as schizophrenia.  This population is generally overweight, with many of the commonly used medications causing weight gain.  Researchers in Maryland conducted a study of 291 obese patients with mental illness, randomizing one group to receive weight loss intervention therapies (i.e. individual and group weight management class, exercise, and dietary changes) with the control group to receive a traditional nutrition regimen.  The intervention group consistently lost weight over the 18-month trial period, showing that these patients can be successful in losing weight when lifestyle interventions are made.  In what other patient populations have you personally found behavioral modifications to be helpful in weight loss?


To view this article, please visit NEJM.

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