A recent five-year follow-up population-based cohort published in Neurology evaluated the risk of developing of Alzheimer’s Disease in 1,768 women ages 65 years and older who were on hormone replacement therapy during menopause.  Researchers concluded that women who used hormone replacement therapy within 5 years of menopause for at least 10 years had 30% less risk of AD.  However, there was a higher risk of the development of AD associated with the use of a combination of estrogen and progestin.  How will this information effect prescribing of HRT in menopausal women?

For more information, please read the abstract in Neurology.