A retrospective cohort study evaluated 1,072,426 subjects who had received antibiotics and had 2 years of follow-up data available.  Seven hundred forty-eight children developed IBD and although an increased risk was seen throughout childhood, the highest risk occurred in children exposed to antibiotics prior to their first birthday.  In addition, subsequent antibiotic courses increased the IBD risk by 6%.  How do you discuss antibiotic therapy with parents?

For additional information, please see abstract in the journal Pediatrics.