Manufactured by Ironwood and Forest Pharmaceuticals, linaclotide can be used for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation. The first guanylate cyclase agonist, the once-daily capsule is taken 30 minutes prior to the first meal of the day and doses differ based on the condition being treated. The most common side effect reported during clinical trials was diarrhea and a boxed warning prohibits use in patients aged 17 or younger. How many of your patients suffer from these conditions? Do you believe this new therapy may benefit them?
For more information, please visit the FDA.